Board Thread:Game Discussion/@comment-5603871-20131021075944/@comment-11490363-20131022185805

All things being equal, higher defense is a diminishing return compared to attack and health. Doubling defense from 10K to 20K is not as good as increasing attack or HP by say 10K. The formulas are pretty straightforward, ish.

Also remember to spread out your 3 biggest HP bosses across your trios to maximize the lifetime of your trios and therefore maximize damage.